Patch clamping an introductory guide to patch clamp electrophysiology paperback

In this chapter we give an overview of patch clamping and how the different configurations can be set up and applied to electrophysiological research. Springer Nature is developing a new tool to find and evaluate Protocols.

Learn more. Skip to main content. This service is more advanced with JavaScript available. Advertisement Hide. An Introduction to Patch Clamp Recording. See more. Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses David Vandael et al. References Hodgkin AL, Huxley AF A quantitative description of the membrane current and its application to conduction and excitation in nerve.

J Physiol — Neher E, Sakmann B Noise analysis of drug induced voltage clamp currents in denervated frog muscle fibres. J Physiol — Neher E, Sakmann B, Steinbach JH The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes. Pflugers Arch — Hille B Ion channels of excitable membranes. Pflugers Arch — Molleman A Patch clamping: an introductory guide to patch clamp electrophysiology.

Back cover copy Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology is a concise introduction to the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the fundamentals of the subject, platforms, equipment and environmental control.

This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this important technique, including an overview of membrane biophysics, standard experimental design, data analysis and technical concerns. Aimed at novice and intermediate researchers within neurobiology laboratories, this text will also be of interest to people new to this technique, in universities and research labs as well as research technicians.

A useful reference for undergraduates specialising in neurophysiology, neuropharmacology and applied physiology. Features: A self-contained guide introducing basic principles and practical applications A practical approach to the subject and written in an accessible non-technical style Extensive coverage of recording modes, analysis of results and numerous handy hints on how to avoid common pitfalls.

Table of contents Preface. Basic Theoretical Principles. The Practice of Patch Clamping. Whole-cell Protocols and Data Analysis.

Single-channel Protocols and Data Analysis. Further Reading. This book will explain the basic principles and practical application of patch clamp electrophysiology Written in a non-technical style to ensure its broad appeal to novice users Takes a practical approach This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns.

More details. Areles Molleman 4 books0. Search review text. Noah Moore.